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Published date: March 26, 2025
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SV388 is a cell line derived from the murine fibroblast cells that has gained significant attention in cancer research. Initially isolated in the early 1970s, SV388 is characterized by its unique properties that make it a valuable model for studying the biology of cancer and the underlying mechanisms of tumor progression. The purpose of this article is to provide an overview of the characteristics, applications, and significance of SV388 in cancer research.
At its core, url SV388 is a transformed cell line that originates from Swiss mice. The transformation process involves the incorporation of viral oncogenes, which leads to alterations in the normal cellular pathways and enables unchecked cell proliferation. SV388 cells exhibit features such as anchorage-independent growth, increased metabolic activity, and the ability to form tumors in immunocompromised mouse models, which are hallmarks of cancerous cells.
At its core, url SV388 is a transformed cell line that originates from Swiss mice. The transformation process involves the incorporation of viral oncogenes, which leads to alterations in the normal cellular pathways and enables unchecked cell proliferation. SV388 cells exhibit features such as anchorage-independent growth, increased metabolic activity, and the ability to form tumors in immunocompromised mouse models, which are hallmarks of cancerous cells.
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