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SV388 has several distinguishing features that enhance its suitability as an oncolytic agent. Unlike traditional chemotherapeutic agents, which indiscriminately target both cancerous and healthy cells, SV388 selectively replicates in tumor cells. The virus exploits the altered signaling pathways commonly associated with neoplastic cells, such as dysregulated cell cycle control and attenuated immune responses, leading to tumor lysis without significantly affecting surrounding healthy tissues.
In a series of recent experiments, researchers have demonstrated the efficacy of SV388 in various preclinical models.
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